GTX66146
SEPT5 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX66146
- Zusätzliche Namen:
- septin 5 , CDCREL , CDCREL-1 , CDCREL1 , H5 , HCDCREL-1 , PNUTL1
- Anwendung:
- WB, IHC-P, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant funsion protein containing a sequence corresponding to amino acids 1-369 of human SEPT5 (NP_002679.2).
- Uniprot:
- Q99719
- Synonyme:
- CDCREL;CDCREL-1;CDCREL1;cell division control related protein 1;Cell division control-related protein 1;H5;HCDCREL-1;peanut-like 1;Peanut-like protein 1;platelet glycoprotein Ib beta chain;PNUTL1;SEPT5;septin-5
- Weitere Details:
- This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010]
- Versandbedingungen:
- Blue Ice