GTX66132
XRCC6BP1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX66132
- Zusätzliche Namen:
- ATP23 metallopeptidase and ATP synthase assembly factor homolog , KUB3 , XRCC6BP1
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant funsion protein containing a sequence corresponding to amino acids 1-246 of human ATP23 (NP_150592.1).
- Uniprot:
- Q9Y6H3
- Synonyme:
- Ku70-binding protein 3;KUB3;mitochondrial inner membrane protease ATP23 homolog;XRCC6-binding protein 1;XRCC6BP1
- Weitere Details:
- The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
- Versandbedingungen:
- Blue Ice