GTX66087
Mxi1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX66087
- Zusätzliche Namen:
- MAX interactor 1, dimerization protein , MAD2 , MXD2 , MXI , bHLHc11
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant funsion protein containing a sequence corresponding to amino acids 170-295 of human MXI1 (NP_569157.2).
- Uniprot:
- P50539
- Synonyme:
- bHLHc11;class C basic helix-loop-helix protein 11;MAD2;MAX dimerization protein 2;max-interacting protein 1;Max-related transcription factor;MXD2;MXI
- Weitere Details:
- Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice