Elongin B antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX66010
Zusätzliche Namen:: elongin B , SIII , TCEB2
Anwendung:: WB, IHC-P, IP
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Recombinant funsion protein containing a sequence corresponding to amino acids 1-118 of human TCEB2 (NP_009039.1).
Uniprot:: Q15370
Synonyme:: elongin 18 kDa subunit;elongin-B;elongin, 18-kD subunit;epididymis secretory sperm binding protein;RNA polymerase II transcription factor SIII p18 subunit;RNA polymerase II transcription factor SIII subunit B;SIII;SIII p18;TCEB2;transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B);transcription elongation factor B polypeptide 2;transcription elongation factor B subunit 2
Weitere Details:: This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, Aug 2008]

Versandbedingungen:: Blue Ice