GTX65976
UVRAG antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX65976
- Zusätzliche Namen:
- UV radiation resistance associated , DHTX , VPS38 , p63
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant funsion protein containing a sequence corresponding to amino acids 501-699 of human UVRAG (NP_003360.2).
- Uniprot:
- Q9P2Y5
- Synonyme:
- beclin 1 binding protein;DHTX;disrupted in heterotaxy;p63;UV radiation resistance-associated gene protein;VPS38
- Weitere Details:
- This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice