GTX65528
GNB3 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX65528
- Zusätzliche Namen:
- G protein subunit beta 3 , CSNB1H
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human GNB3 (NP_002066.1).
- Uniprot:
- P16520
- Synonyme:
- CSNB1H;G protein, beta-3 subunit;GTP-binding regulatory protein beta-3 chain;guanine nucleotide binding protein (G protein), beta polypeptide 3;guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3;guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;hypertension associated protein;transducin beta chain 3
- Weitere Details:
- Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014]
- Versandbedingungen:
- Blue Ice