GTX64947
MTMR3 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX64947
- Zusätzliche Namen:
- myotubularin related protein 3 , FYVE-DSP1 , ZFYVE10
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 640-810 of human MTMR3 (NP_066576.1).
- Uniprot:
- Q13615
- Synonyme:
- FYVE (Fab1 YGLO23 Vsp27 EEA1 domain) dual-specificity protein phosphatase;FYVE domain-containing dual specificity protein phosphatase 1;FYVE-DSP1;myotubularin-related protein 3;phosphatidylinositol-3-phosphate phosphatase;phosphatidylinositol-3,5-bisphosphate 3-phosphatase;ZFYVE10;zinc finger FYVE domain-containing protein 10;zinc finger, FYVE domain containing 10
- Weitere Details:
- This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice