GTX64946
SNAPIN antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX64946
- Zusätzliche Namen:
- SNAP associated protein , BLOC1S7 , BLOS7 , BORCS3 , SNAPAP
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human SNAPIN (NP_036569.1).
- Uniprot:
- O95295
- Synonyme:
- biogenesis of lysosomal organelles complex-1, subunit 7;biogenesis of lysosome-related organelles complex 1 subunit 7;BLOC-1 related complex subunit 3;BLOC-1 subunit 7;BLOC1S7;BLOS7;BORCS3;SNAP-25-binding protein;SNAPAP;SNARE associated protein snapin;SNARE-associated protein Snapin;synaptosomal-associated protein 25-binding protein
- Weitere Details:
- The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
- Versandbedingungen:
- Blue Ice