GTX64854
SUCLA2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX64854
- Zusätzliche Namen:
- succinate-CoA ligase ADP-forming beta subunit , A-BETA , A-SCS , MTDPS5 , SCS-betaA
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SUCLA2 (NP_003841.1).
- Uniprot:
- Q9P2R7
- Synonyme:
- A-BETA;A-SCS;ATP-specific succinyl-CoA synthetase subunit beta;ATP-specific succinyl-CoA synthetase, beta subunit;LINC00444;long intergenic non-protein coding RNA 444;mitochondrial succinyl-CoA ligase [ADP-forming] subunit beta;MTDPS5;renal carcinoma antigen NY-REN-39;SCS-betaA;succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial;succinate-CoA ligase ADP-forming beta subunit;succinate-CoA ligase beta subunit;succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial;succinyl-CoA synthetase beta-A chain
- Weitere Details:
- Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice