GTX647260
Neuroserpin antibody [HL5935]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX647260
- Zusätzliche Namen:
- serpin family I member 1 , PI12 , neuroserpin
- Anwendung:
- WB, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Synthetic peptide of human Neuroserpin.
- Klon:
- HL5935
- Uniprot:
- Q99574
- Synonyme:
- HNS-S1;HNS-S2;neuroserpin;peptidase inhibitor 12;PI-12;PI12;serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1;serpin I1;serpin peptidase inhibitor clade I member 1;serpin peptidase inhibitor, clade I (neuroserpin), member 1;truncated HNS-T
- Weitere Details:
- This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice