GTX64724
Activin Receptor Type IIA antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX64724
- Zusätzliche Namen:
- activin A receptor type 2A , ACTRII , ACVR2
- Anwendung:
- WB, IHC-P, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.09% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-140 of human ACVR2A (NP_001607.1).
- Uniprot:
- P27037
- Synonyme:
- activin A receptor, type IIA;Activin receptor type IIA;activin receptor type-2A;ACTRII;ACVR2
- Weitere Details:
- This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013]
- Versandbedingungen:
- Blue Ice