GTX64719
LMAN1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX64719
- Zusätzliche Namen:
- lectin, mannose binding 1 , ERGIC-53 , ERGIC53 , F5F8D , FMFD1 , MCFD1 , MR60 , gp58
- Anwendung:
- WB, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 270-480 of human LMAN1 (NP_005561.1).
- Uniprot:
- P49257
- Synonyme:
- endoplasmic reticulum-golgi intermediate compartment protein 53;ER-Golgi intermediate compartment 53 kDa protein;ERGIC-53;ERGIC53;F5F8D;FMFD1;gp58;intracellular mannose-specific lectin MR60;Lectin mannose-binding 1;MCFD1;MR60;protein ERGIC-53
- Weitere Details:
- The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency. [provided by RefSeq, Jul 2015]
- Versandbedingungen:
- Blue Ice