GTX64671
USP5 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX64671
- Zusätzliche Namen:
- ubiquitin specific peptidase 5 , ISOT
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human USP5 (NP_003472.2).
- Uniprot:
- P45974
- Synonyme:
- deubiquitinating enzyme 5;isopeptidase T;ISOT;testicular tissue protein Li 218;ubiquitin carboxyl-terminal hydrolase 5;ubiquitin isopeptidase T;ubiquitin specific protease 5 (isopeptidase T);ubiquitin thioesterase 5;ubiquitin thiolesterase 5;ubiquitin-specific protease-5 (ubiquitin isopeptidase T);ubiquitin-specific-processing protease 5
- Weitere Details:
- Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010]
- Versandbedingungen:
- Blue Ice