GTX64632
IL5 Receptor alpha antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX64632
- Zusätzliche Namen:
- interleukin 5 receptor subunit alpha , CD125 , CDw125 , HSIL5R3 , IL5R
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-335 of human IL5RA (NP_783855.1).
- Uniprot:
- Q01344
- Synonyme:
- CD125;CD125 antigen;CDw125;HSIL5R3;IL-5 receptor subunit alpha;IL-5R subunit alpha;IL5R;interleukin 5 receptor type 3;interleukin 5 receptor, alpha;interleukin-5 receptor alpha chain;interleukin-5 receptor subunit alpha
- Weitere Details:
- The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011]
- Versandbedingungen:
- Blue Ice