GTX645733
IKZF3 antibody [HL5295]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX645733
- Zusätzliche Namen:
- IKAROS family zinc finger 3 , AIO , AIOLOS , ZNFN1A3
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Synthetic peptide of human IKZF3.
- Klon:
- HL5295
- Uniprot:
- Q9UKT9
- Synonyme:
- AIO;AIOLOS;Ikaros family zinc finger protein 3;IMD84;zinc finger DNA binding protein Aiolos;zinc finger protein Aiolos;zinc finger protein, subfamily 1A, 3 (Aiolos);ZNFN1A3
- Weitere Details:
- This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]
- Versandbedingungen:
- Blue Ice