GTX64568
PHLPP1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX64568
- Zusätzliche Namen:
- PH domain and leucine rich repeat protein phosphatase 1 , PHLPP , PLEKHE1 , PPM3A , SCOP
- Anwendung:
- WB, IHC-P, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1508-1717 of human PHLPP1 (NP_919431.2).
- Uniprot:
- O60346
- Synonyme:
- PH domain leucine-rich repeat-containing protein phosphatase 1;PH domain-containing family E member 1;PHLPP;pleckstrin homology domain containing, family E (with leucine rich repeats) member 1;Pleckstrin homology domain-containing family E member 1;PLEKHE1;PPM3A;protein phosphatase, Mg2+/Mn2+ dependent 3A;SCN circadian oscillatory protein;SCOP;suprachiasmatic nucleus circadian oscillatory protein
- Weitere Details:
- This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011]
- Versandbedingungen:
- Blue Ice