GTX64556
MKL1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX64556
- Zusätzliche Namen:
- myocardin related transcription factor A , BSAC , MAL , MKL , MKL1 , MRTF-A
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human MKL1 (NP_065882.1).
- Uniprot:
- Q969V6
- Synonyme:
- basic, SAP and coiled-coil domain;BSAC;MAL;megakaryoblastic leukemia (translocation) 1;megakaryoblastic leukemia 1 protein;megakaryocytic acute leukemia protein;MKL;MKL/myocardin-like protein 1;MKL1;MRTF-A;myocardin-related transcription factor A
- Weitere Details:
- The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
- Versandbedingungen:
- Blue Ice