GTX64541
CRLF2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX64541
- Zusätzliche Namen:
- cytokine receptor like factor 2 , CRL2 , CRLF2Y , TSLPR
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 23-231 of human CRLF2 (NP_071431.2).
- Uniprot:
- Q9HC73
- Synonyme:
- CRL2;CRLF2Y;cytokine receptor CRL2 precusor;Cytokine receptor-like 2;cytokine receptor-like factor 2;IL-XR;thymic stromal lymphopoietin protein receptor;thymic stromal-derived lymphopoietin receptor;TSLP receptor;TSLPR
- Weitere Details:
- This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]
- Versandbedingungen:
- Blue Ice