GTX64506
PHOX2B antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX64506
- Zusätzliche Namen:
- paired like homeobox 2B , CCHS , NBLST2 , NBPhox , PMX2B
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human PHOX2B (NP_003915.2).
- Uniprot:
- Q99453
- Synonyme:
- CCHS;NBLST2;NBPhox;neuroblastoma paired-type homeobox protein;neuroblastoma Phox;paired like homeobox2B;paired mesoderm homeobox 2b;paired mesoderm homeobox protein 2B;Paired-like homeobox 2B;PHOX2B homeodomain protein;PMX2B
- Weitere Details:
- The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome. [provided by RefSeq, Jul 2016]
- Versandbedingungen:
- Blue Ice