GTX64490
HSP22 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX64490
- Zusätzliche Namen:
- heat shock protein family B (small) member 8 , CMT2L , DHMN2 , E2IG1 , H11 , HMN2 , HMN2A , HSP22
- Anwendung:
- WB, IHC-P, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-196 of human HSPB8 (NP_055180.1).
- Uniprot:
- Q9UJY1
- Synonyme:
- alpha-crystallin C chain;CMT2L;DHMN2;E2-induced gene 1 protein;E2IG1;H11;heat shock 22kDa protein 8;heat shock 27kDa protein 8;heat shock protein beta-8;HMN2;HMN2A;HSP22;protein kinase H11;small stress protein-like protein HSP22
- Weitere Details:
- The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice