GTX64412
LRP5 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX64412
- Zusätzliche Namen:
- LDL receptor related protein 5 , BMND1 , EVR1 , EVR4 , HBM , LR3 , LRP-5 , LRP-7 , LRP7 , OPPG , OPS , OPTA1 , PCLD4 , VBCH2
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.05% ProClin 300.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1250 of human LRP5 (NP_002326.2).
- Uniprot:
- O75197
- Synonyme:
- BMND1;EVR1;EVR4;HBM;low density lipoprotein receptor-related protein 5;low density lipoprotein receptor-related protein 7;low-density lipoprotein receptor-related protein 5;LR3;LRP-5;LRP-7;LRP7;OPPG;OPS;OPTA1;PCLD4;VBCH2
- Weitere Details:
- This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
- Versandbedingungen:
- Blue Ice