GTX643563
APOBEC3A antibody [HL4316]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX643563
- Zusätzliche Namen:
- apolipoprotein B mRNA editing enzyme catalytic subunit 3A , A3A , ARP3 , PHRBN , bK150C2.1
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Synthetic peptide of human APOBEC3A.
- Klon:
- HL4316
- Uniprot:
- P31941
- Synonyme:
- A3A;APOBEC3A;apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A;ARP3;bK150C2.1;DNA dC->dU-editing enzyme APOBEC-3A;phorbolin-1;PHRBN;probable DNA dC->dU-editing enzyme APOBEC-3A
- Weitere Details:
- This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
- Versandbedingungen:
- Blue Ice