GTX64349
TSG101 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX64349
- Zusätzliche Namen:
- tumor susceptibility 101 , TSG10 , VPS23
- Anwendung:
- WB, IHC-P, IP
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human TSG101 (NP_006283.1).
- Uniprot:
- Q99816
- Synonyme:
- ESCRT-I complex subunit TSG101;TSG10;tumor susceptibility gene 10;tumor susceptibility gene 101;tumor susceptibility gene 101 protein;tumor susceptibility protein;VPS23
- Weitere Details:
- The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice