![GITR antibody [HL3289]](https://www.genetex.com/upload/website/prouct_img/normal/GTX640943/GTX640943_T-45530_20240913_WB_Fraction_24091901_489.webp)
GTX640943
GITR antibody [HL3289]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX640943
- Zusätzliche Namen:
- TNF receptor superfamily member 18 , AITR , CD357 , GITR , GITR-D
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Recombinant protein encompassing a sequence within the Extracellular domain of human GITR. The exact sequence is proprietary.
- Klon:
- HL3289
- Uniprot:
- Q9Y5U5
- Synonyme:
- activation-inducible TNFR family receptor;AITR;CD357;ENERGEN;GITR;GITR-D;glucocorticoid-induced TNFR-related protein;TNF receptor superfamily activation-inducible protein;tumor necrosis factor receptor superfamily member 18
- Weitere Details:
- This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
- Versandbedingungen:
- Blue Ice