HLA-A2 antibody [BB7.2]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX639675
Zusätzliche Namen:: major histocompatibility complex, class I, A , HLAA
Anwendung:: Flow Cytometry
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 20% Glycerol, no preservatives.
Immunogen:: The immunogen used to generate this antibody corresponds to human HLA-A2.
Klon:: BB7.2
Uniprot:: P04439, P30443
Synonyme:: HLA class I histocompatibility antigen, A alpha chain;HLA class I histocompatibility antigen, A-1 alpha chain;HLAA;Human leukocyte antigen A;leukocyte antigen class I-A;MHC class I antigen A*1;MHC class I antigen A*3;MHC class I antigen HLA-A heavy chain
Weitere Details:: HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice