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GTX639039

Fibrillarin + FBLL1 antibody [HL2588]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX639039
Zusätzliche Namen:
fibrillarin , FIB , FLRN , Nop1 , RNU3IP1
Anwendung:
WB, IHC-P, IF, ICC
Konzentration:
1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
PBS, no preservatives.
Immunogen:
Recombinant fragment of human fibrillarin.
Klon:
HL2588
Uniprot:
P22087
Synonyme:
34 kDa nucleolar scleroderma antigen;34-kD nucleolar scleroderma antigen;FIB;FLRN;histone-glutamine methyltransferase;Nop1;RNA, U3 small nucleolar interacting protein 1;RNU3IP1;rRNA 2'-O-methyltransferase fibrillarin;U6 snRNA 2'-O-methyltransferase fibrillarin
Weitere Details:
This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008]
Versandbedingungen:
Blue Ice