GLP1R antibody [HL2297]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX638352
Zusätzliche Namen:: glucagon like peptide 1 receptor , GLP-1 , GLP-1-R , GLP-1R
Anwendung:: IHC-P
Konzentration:: 2 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: PBS, no preservatives.
Immunogen:: Synthetic peptide encompassing a sequence within the Extracellular domain human of GLP1R. The exact sequence is proprietary.
Klon:: HL2297
Uniprot:: P43220
Synonyme:: GLP-1;GLP-1 receptor;GLP-1-R;GLP-1R;GLP1 receptor;glucagon-like peptide 1 receptor;seven transmembrane helix receptor
Weitere Details:: This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]

Versandbedingungen:: Blue Ice