CARD10 antibody [HL2261]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX638313
Zusätzliche Namen:: caspase recruitment domain family member 10 , BIMP1 , CARMA3
Anwendung:: WB
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant fragment of human CARD10.
Klon:: HL2261
Uniprot:: Q9BWT7
Synonyme:: Bcl10 binding protein and activator of NFKB;BIMP1;CARD-containing MAGUK 3 protein;CARD-containing MAGUK protein 3;carma 3;CARMA3;caspase recruitment domain-containing protein 10
Weitere Details:: The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008]