IGF1R beta antibody [HL1958]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX637795
Zusätzliche Namen:: insulin like growth factor 1 receptor , CD221 , IGFIR , IGFR , JTK13
Anwendung:: WB, IHC-P
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant protein encompassing a sequence within the Extracellular domain of human IGF1R beta. The exact sequence is proprietary.
Klon:: HL1958
Uniprot:: P08069
Synonyme:: CD221;IGF-I receptor;IGFIR;IGFR;insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;JTK13;soluble IGF1R variant 1;soluble IGF1R variant 2
Weitere Details:: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]