PGK1 + PGK2 antibody [HL1775]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX637427
Zusätzliche Namen:: phosphoglycerate kinase 1 , HEL-S-68p , MIG10 , PGKA
Anwendung:: WB, IHC-P
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Fish, Human, Mouse, Rat
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant fragment of human PGK1.
Klon:: HL1775
Uniprot:: P00558
Synonyme:: cell migration-inducing gene 10 protein;epididymis secretory sperm binding protein Li 68p;HEL-S-68p;MIG10;PGKA;phosphoglycerate kinase 1;primer recognition protein 2;PRP 2
Weitere Details:: The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]

Versandbedingungen:: Blue Ice