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GTX637282

TCEB1 antibody [HL1683]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX637282
Zusätzliche Namen:
elongin C , SIII , TCEB1
Anwendung:
WB, IHC-P
Konzentration:
1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Canine, Human, Mouse, Rat, Feline, Insect/Arthropod
Buffer:
PBS, no preservatives.
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human TCEB1. The exact sequence is proprietary.
Klon:
HL1683
Uniprot:
Q15369
Synonyme:
elongin 15 kDa subunit;elongin-C;RNA polymerase II transcription factor SIII subunit C;SIII;SIII p15;TCEB1;transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C);transcription elongation factor B polypeptide 1;transcription elongation factor B subunit 1
Weitere Details:
This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
Versandbedingungen:
Blue Ice