NDUFV1 antibody [HL1600]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX637079
Zusätzliche Namen:: NADH:ubiquinone oxidoreductase core subunit V1 , CI-51K , CI51KD , MC1DN4 , UQOR1
Anwendung:: WB, IHC-P
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Rat
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human NDUFV1. The exact sequence is proprietary.
Klon:: HL1600
Uniprot:: P49821
Synonyme:: CI-51K;CI51KD;complex I 51 kda subunit;complex I 51kDa subunit;Complex I-51kD;complex I, mitochondrial respiratory chain;MC1DN4;mitochondrial NADH dehydrogenase ubiquinone flavoprotein 1;mitochondrial NADH:ubiquinone oxidoreductase 51 kda subunit;NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa;NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial;NADH dehydrogenase flavoprotein 1;NADH-ubiquinone oxidoreductase 51 kDa subunit;UQOR1
Weitere Details:: The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]

Versandbedingungen:: Blue Ice