COL4A1 antibody [HL1351]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX636771
Zusätzliche Namen:: collagen type IV alpha 1 chain , BSVD , RATOR
Anwendung:: WB, IHC-P, IF, ICC
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant protein encompassing a sequence within the N-terminus of human COL4A1. The exact sequence is proprietary.
Klon:: HL1351
Uniprot:: P02462
Synonyme:: arresten;BSVD;BSVD1;COL4A1 NC1 domain;COL4A1s;collagen alpha-1(IV) chain;collagen IV, alpha-1 polypeptide;collagen of basement membrane, alpha-1 chain;PADMAL;RATOR
Weitere Details:: This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Versandbedingungen:: Blue Ice