GAD65 antibody [HL1187]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX636493
Zusätzliche Namen:: glutamate decarboxylase 2 , GAD65
Anwendung:: WB, IHC-P, IHC-Fr, IF, ICC
Konzentration:: 0.2 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Canine, Fish, Human, Mouse, Rat, Feline
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant protein encompassing a sequence within the C-terminus region of human GAD65. The exact sequence is proprietary.
Klon:: HL1187
Uniprot:: Q05329
Synonyme:: 65 kDa glutamic acid decarboxylase;GAD-65;GAD65;glutamate decarboxylase 2;glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa);Glutamate decarboxylase 65 kDa isoform;Glutamate decarboxylase-2 (pancreas)
Weitere Details:: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]

Versandbedingungen:: Blue Ice