ZO-1 antibody [HL1133]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX636399
Zusätzliche Namen:: tight junction protein 1 , ZO-1
Anwendung:: WB, IF, ICC
Konzentration:: 2 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant protein encompassing a sequence within the N-terminus region of human ZO-1. The exact sequence is proprietary.
Klon:: HL1133
Uniprot:: Q07157
Synonyme:: Tight junction protein 1;tight junction protein ZO-1;ZO-1;zona occludens 1;Zona occludens protein 1;zonula occludens 1 protein;Zonula occludens protein 1
Weitere Details:: This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]

Versandbedingungen:: Blue Ice