Nanog antibody [GT3312]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX627421
Zusätzliche Namen:: Nanog homeobox
Anwendung:: Flow Cytometry, WB
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human NANOG. The exact sequence is proprietary.
Klon:: GT3312
Uniprot:: Q9H9S0
Synonyme:: homeobox protein NANOG;homeobox transcription factor Nanog;homeobox transcription factor Nanog-delta 48
Weitere Details:: Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation.

Versandbedingungen:: Blue Ice