Neuropeptide Y antibody [8]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX60971
Zusätzliche Namen:: neuropeptide Y , PYY4
Anwendung:: ELISA, IHC-P, IHC-Fr, IF, ICC
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: 2-8[o]C
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse, Rat
Buffer:: 10mM Phosphate, 500mM NaCl, 15mM Sodium azide.
Immunogen:: Synthetic human/rat neuropeptide Y
Klon:: 8
Uniprot:: P01303
Synonyme:: prepro-neuropeptide Y;pro-neuropeptide Y;PYY4
Weitere Details:: This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]