GPNMB antibody [7C10E5]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX60790
Zusätzliche Namen:: glycoprotein nmb , HGFIN , NMB , PLCA3
Anwendung:: ELISA, WB, IHC-P
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 0.05% Sodium azide.
Immunogen:: Purified recombinant fragment of human GPNMB (AA: 31-260) expressed in E. Coli.
Klon:: 7C10E5
Uniprot:: Q14956
Synonyme:: glycoprotein (transmembrane) nmb;glycoprotein nmb-like protein;glycoprotein nonmetastatic melanoma protein B;hematopoietic growth factor inducible neurokinin-1 type;HGFIN;NMB;osteoactivin;PLCA3;transmembrane glycoprotein HGFIN;transmembrane glycoprotein NMB
Weitere Details:: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]