WHSC2 antibody [6B11H8]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX60733
Zusätzliche Namen:: negative elongation factor complex member A , NELF-A , P/OKcl.15 , WHSC2
Anwendung:: ELISA, Flow Cytometry, WB, IHC-P, IF, ICC
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Rat
Buffer:: PBS, 0.05% Sodium azide.
Immunogen:: Purified recombinant fragment of human WHSC2 (AA: 280-511) expressed in E. Coli.
Klon:: 6B11H8
Uniprot:: Q9H3P2
Synonyme:: negative elongation factor A;NELF-A;P/OKcl.15;WHSC2;wolf-Hirschhorn syndrome candidate 2 protein
Weitere Details:: This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice