PCNA antibody [7H4F8]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX60692
Zusätzliche Namen:: proliferating cell nuclear antigen , ATLD2
Anwendung:: ELISA, Flow Cytometry, WB, IHC-P
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 0.05% Sodium azide.
Immunogen:: Purified recombinant fragment of human PCNA (AA: 53-196 ) expressed in E. Coli.
Klon:: 7H4F8
Uniprot:: P12004
Synonyme:: ATLD2;cyclin;DNA polymerase delta auxiliary protein;proliferating cell nuclear antigen
Weitere Details:: The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]