RUNX3 antibody [2B3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX60639
Zusätzliche Namen:: runt related transcription factor 3 , AML2 , CBFA3 , PEBP2aC
Anwendung:: ELISA, Flow Cytometry, WB, IHC-P, IF, ICC
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse
Buffer:: PBS, 0.05% Sodium azide.
Immunogen:: Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. Coli.
Klon:: 2B3
Uniprot:: Q13761
Synonyme:: acute myeloid leukemia 2 protein;acute myeloid leukemia gene 2;AML2;CBF-alpha-3;CBFA3;core-binding factor subunit alpha-3;core-binding factor, runt domain, alpha subunit 3;oncogene AML-2;PEA2 alpha C;PEBP2 alpha C;PEBP2aC;polyomavirus enhancer-binding protein 2 alpha C subunit;runt related transcription factor 3;runt-related transcription factor 3;SL3-3 enhancer factor 1 alpha C subunit;SL3/AKV core-binding factor alpha C subunit;transcription factor AML2
Weitere Details:: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice