PDX1 antibody [5A5]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX60573
Zusätzliche Namen:: pancreatic and duodenal homeobox 1 , GSF , IDX-1 , IPF1 , IUF1 , MODY4 , PAGEN1 , PDX-1 , STF-1
Anwendung:: ELISA, Flow Cytometry, WB
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 0.05% Sodium azide.
Immunogen:: Purified recombinant fragment of human PDX1 expressed in E. Coli.
Klon:: 5A5
Uniprot:: P52945
Synonyme:: glucose-sensitive factor;GSF;IDX-1;Insulin promoter factor 1;insulin promoter factor 1, homeodomain transcription factor;insulin upstream factor 1;IPF-1;IPF1;islet/duodenum homeobox-1;IUF-1;IUF1;MODY4;PAGEN1;pancreas/duodenum homeobox protein 1;pancreatic-duodenal homeobox factor 1;PDX-1;somatostatin transcription factor 1;somatostatin-transactivating factor 1;STF-1
Weitere Details:: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice