NQO1 antibody [1A11]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX60524
Zusätzliche Namen:: NAD(P)H quinone dehydrogenase 1 , DHQU , DIA4 , DTD , NMOR1 , NMORI , QR1
Anwendung:: ELISA, Flow Cytometry, WB
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of human NQO1 expressed in E. Coli.
Klon:: 1A11
Uniprot:: P15559
Synonyme:: azoreductase;DHQU;DIA4;diaphorase (NADH/NADPH) (cytochrome b-5 reductase);diaphorase-4;dioxin-inducible 1;DT-diaphorase;DTD;menadione reductase;NAD(P)H dehydrogenase [quinone] 1;NAD(P)H dehydrogenase, quinone 1;NAD(P)H:menadione oxidoreductase 1;NAD(P)H:Quinone acceptor oxidoreductase type 1;NAD(P)H:quinone oxidoreductase 1;NAD(P)H:quinone oxireductase;NMOR1;NMORI;phylloquinone reductase;QR1;quinone reductase 1
Weitere Details:: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice