LIMS1 antibody [5G7]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX60472
Zusätzliche Namen:: LIM zinc finger domain containing 1 , PINCH , PINCH-1 , PINCH1
Anwendung:: ELISA, Flow Cytometry, WB, IF, ICC
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of human LIMS1 expressed in E. Coli.
Klon:: 5G7
Uniprot:: P48059
Synonyme:: LIM and senescent cell antigen-like domains 1;LIM and senescent cell antigen-like-containing domain protein 1;LIM-type zinc finger domains 1;particularly interesting new Cys-His protein 1;PINCH;PINCH-1;PINCH1;renal carcinoma antigen NY-REN-48;senescent cell antigen
Weitere Details:: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

Versandbedingungen:: Blue Ice