BLNK antibody [5G9]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX60463
Zusätzliche Namen:: B cell linker , AGM4 , BASH , BLNK-S , LY57 , SLP-65 , SLP65 , bca
Anwendung:: ELISA, Flow Cytometry, WB, IHC-P, IF, ICC
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of human BLNK expressed in E. Coli.
Klon:: 5G9
Uniprot:: Q8WV28
Synonyme:: AGM4;B cell adaptor containing SH2 domain;B-cell activation;B-cell adapter containing a SH2 domain protein;B-cell adapter containing a Src homology 2 domain protein;B-cell linker protein;BASH;bca;BLNK-S;cytoplasmic adapter protein;LY57;SLP-65;SLP65;Src homology [SH2] domain-containing leukocyte protein of 65 kD;Src homology 2 domain-containing leukocyte protein of 65 kDa
Weitere Details:: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]

Versandbedingungen:: Blue Ice