CDK5 antibody [4E4]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX60441
Zusätzliche Namen:: cyclin dependent kinase 5 , LIS7 , PSSALRE
Anwendung:: ELISA, Flow Cytometry, WB, IHC-P, IF, ICC
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Rat
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of human CDK5 expressed in E. Coli.
Klon:: 4E4
Uniprot:: Q00535
Synonyme:: cell division protein kinase 5;cyclin-dependent-like kinase 5;epididymis secretory sperm binding protein;LIS7;protein kinase CDK5 splicing;PSSALRE;serine/threonine-protein kinase PSSALRE;tau protein kinase II catalytic subunit;TPKII catalytic subunit
Weitere Details:: This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]

Versandbedingungen:: Blue Ice