GTX60368
RFXAP antibody - ChIP grade
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX60368
- Zusätzliche Namen:
- regulatory factor X associated protein
- Anwendung:
- ChIP
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.05% Sodium azide, 0.05% ProClin 300.
- Immunogen:
- RFXAP (Regulatory factor X-associated protein), using the recombinant protein.
- Uniprot:
- O00287
- Synonyme:
- regulatory factor X-associated protein;RFX DNA-binding complex 36 kDa subunit;RFX-associated protein
- Weitere Details:
- Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice