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GTX60366
HDAC3 antibody [GT9007]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX60366
- Zusätzliche Namen:
- histone deacetylase 3 , HD3 , KDAC3 , RPD3 , RPD3-2
- Anwendung:
- ChIP, IF, ICC
- Konzentration:
- 2 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.05% Sodium azide, 0.05% ProClin 300.
- Immunogen:
- Human HDAC3 (Histone deacetylase 3), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal region of the protein.
- Klon:
- GT9007
- Uniprot:
- O15379
- Synonyme:
- HD3;histone deacetylase 3;KDAC3;RPD3;RPD3-2;SMAP45
- Weitere Details:
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice