GTX57752
NALP6 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX57752
- Zusätzliche Namen:
- NLR family pyrin domain containing 6 , AVR , CLR11.4 , NALP6 , NAVR , NAVR/AVR , PAN3 , PYPAF5
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a sequence within amino acids 100-200 of human NALP6 (NP_001263629.1).
- Uniprot:
- P59044
- Synonyme:
- angiotensin II/vasopressin receptor;AVR;CLR11.4;NACHT, leucine rich repeat and PYD containing 6;NACHT, LRR and PYD domains-containing protein 6;NALP6;NAVR;NAVR/AVR;nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 6;PAN3;PYPAF5;PYRIN-containing APAF1-like protein 5
- Weitere Details:
- The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]
- Versandbedingungen:
- Blue Ice