ALDH2 antibody [AT2C10]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX57696
Zusätzliche Namen:: aldehyde dehydrogenase 2 family member , ALDH2 , ALDHE2 , ALDHI , ALDM , aldehyde dehydrogenase 2 family (mitochondrial)
Anwendung:: WB, IF, ICC
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse
Buffer:: PBS, 10% Glycerol, 0.02% Sodium azide.
Immunogen:: The clone AT2C10 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ALDH4 protein.
Klon:: AT2C10
Uniprot:: P05091
Synonyme:: acetaldehyde dehydrogenase 2;aldehyde dehydrogenase 2 family (mitochondrial);aldehyde dehydrogenase, mitochondrial;ALDH class 2;ALDH-E2;ALDHI;ALDM;epididymis secretory sperm binding protein;liver mitochondrial ALDH;nucleus-encoded mitochondrial aldehyde dehydrogenase 2
Weitere Details:: This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2016]

Versandbedingungen:: Blue Ice